Anti-alpha 1 Fetoprotein antibody (FITC) (ab87636)

Overview

  • Product nameAnti-alpha 1 Fetoprotein antibody (FITC)
    See all alpha 1 Fetoprotein primary antibodies
  • Description
    Rabbit polyclonal to alpha 1 Fetoprotein (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Specificityab87636 does not cross react to human lactoferrin, human serum albumin, bovine lactoferrin or bovine serum albumin and other cellular proteins.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human alpha 1 Fetoprotein. Purified human alpha Fetoprotein.

Properties

Applications

Our Abpromise guarantee covers the use of ab87636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 69 kDa.
ELISA 1/10000.

Target

  • FunctionBinds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
  • Tissue specificityPlasma. Synthesized by the fetal liver and yolk sac.
  • Sequence similaritiesBelongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • Developmental stageOccurs in the plasma of fetuses more than 4 weeks old, reaches the highest levels during the 12th-16th week of gestation, and drops to trace amounts after birth. The serum level in adults is usually less than 40 ng/ml. AFP occurs also at high levels in the plasma and ascitic fluid of adults with hepatoma.
  • Post-translational
    modifications
    Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
    Sulfated.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Afp antibody
    • Alpha fetoglobulin antibody
    • Alpha fetoprotein antibody
    • Alpha fetoprotein precursor antibody
    • Alpha-1-fetoprotein antibody
    • Alpha-fetoglobulin antibody
    • Alpha-fetoprotein antibody
    • alpha-fetoprotein, Hereditary persistence of, included antibody
    • FETA antibody
    • FETA_HUMAN antibody
    • Hereditary persistence of alpha fetoprotein antibody
    • HPAFP antibody
    see all

References for Anti-alpha 1 Fetoprotein antibody (FITC) (ab87636)

ab87636 has not yet been referenced specifically in any publications.

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I contacted the specialists in the lab and they provide the following information:

1.) The ratio of FITC to Ig is between 10:1 and 20:1.

2.) There is no modification on IgG to create additional ...

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