Anti-Alpha 2 Antiplasmin antibody (ab106821)

Overview

  • Product nameAnti-Alpha 2 Antiplasmin antibody
    See all Alpha 2 Antiplasmin primary antibodies
  • Description
    Goat polyclonal to Alpha 2 Antiplasmin
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-KDFLQSLKGFPRGDK

    , corresponding to internal sequence amino acids 454-468 of Human Alpha 2 Antiplasmin (NP_000925.2.).

  • Positive control
    • Human duodenum and ileum lysates; Human Liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab106821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa.
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionSerine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Involvement in diseaseDefects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
  • Sequence similaritiesBelongs to the serpin family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • A2AP antibody
    • A2AP_HUMAN antibody
    • AAP antibody
    • Alpha 2 antiplasmin antibody
    • Alpha 2 antiplasmin pigment epithelium derived factor antibody
    • Alpha 2 AP antibody
    • ALPHA 2 PI antibody
    • Alpha 2 plasmin inhibitor antibody
    • Alpha 2 plasmin inhibitor deficiency antibody
    • Alpha-2-antiplasmin antibody
    • Alpha-2-AP antibody
    • Alpha-2-PI antibody
    • Alpha-2-plasmin inhibitor antibody
    • Antiplasmin deficiency antibody
    • API antibody
    • Plasmin inhibitor deficiency antibody
    • PLI antibody
    • Serine (or cysteine) peptidase inhibitor, clade F, member 2 antibody
    • Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c antibody
    • Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibody
    • Serine (Or cysteine) proteinase inhibitor, clade F, member 2 antibody
    • Serine or cysteine peptidase inhibitor clade F member 2 antibody
    • Serpin F2 antibody
    • Serpin peptidase inhibitor clade F antibody
    • Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibody
    • SERPINF2 antibody
    see all

Anti-Alpha 2 Antiplasmin antibody images

  • Anti-Alpha 2 Antiplasmin antibody (ab106821) at 0.1 µg/ml (for 1 hour) + Human Duodenum lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 55 kDa
  • ab106821 at 3.8µg/ml staining Alpha 2 Antiplasmin in Human Liver by Immunohistochemistry, Paraffin-embedded tissue.

References for Anti-Alpha 2 Antiplasmin antibody (ab106821)

ab106821 has not yet been referenced specifically in any publications.

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