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Goat polyclonal to Alpha 2 Antiplasmin
, corresponding to internal sequence amino acids 454-468 of Human Alpha 2 Antiplasmin (NP_000925.2.).
- Human duodenum and ileum lysates; Human Liver tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Immunogen affinity purified
ab106821 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa.
||Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Expressed by the liver and secreted in plasma.
Involvement in disease
Defects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
Belongs to the serpin family.
Information by UniProt
- A2AP antibody
- A2AP_HUMAN antibody
- AAP antibody
Western blot - Alpha 2 Antiplasmin antibody (ab106821)
Anti-Alpha 2 Antiplasmin antibody (ab106821) at 0.1 µg/ml (for 1 hour) + Human Duodenum lysate in RIPA buffer at 35 µg
Developed using the ECL technique
Predicted band size : 55 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alpha 2 Antiplasmin antibody (ab106821)
ab106821 at 3.8µg/ml staining Alpha 2 Antiplasmin in Human Liver by Immunohistochemistry, Paraffin-embedded tissue.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"