Overview

  • Product nameAnti-Alpha 2 Antiplasmin antibody
    See all Alpha 2 Antiplasmin primary antibodies
  • Description
    Rabbit polyclonal to Alpha 2 Antiplasmin
  • SpecificityThis antibody is specific for Alpha 2 Antiplasmin.
  • Tested applicationsSuitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native Alpha 2 Antiplasmin protein (purified) (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab48591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • FunctionSerine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Involvement in diseaseDefects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
  • Sequence similaritiesBelongs to the serpin family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • A2AP antibody
    • A2AP_HUMAN antibody
    • AAP antibody
    • Alpha 2 antiplasmin antibody
    • Alpha 2 antiplasmin pigment epithelium derived factor antibody
    • Alpha 2 AP antibody
    • ALPHA 2 PI antibody
    • Alpha 2 plasmin inhibitor antibody
    • Alpha 2 plasmin inhibitor deficiency antibody
    • Alpha-2-antiplasmin antibody
    • Alpha-2-AP antibody
    • Alpha-2-PI antibody
    • Alpha-2-plasmin inhibitor antibody
    • Antiplasmin deficiency antibody
    • API antibody
    • Plasmin inhibitor deficiency antibody
    • PLI antibody
    • Serine (or cysteine) peptidase inhibitor, clade F, member 2 antibody
    • Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c antibody
    • Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibody
    • Serine (Or cysteine) proteinase inhibitor, clade F, member 2 antibody
    • Serine or cysteine peptidase inhibitor clade F member 2 antibody
    • Serpin F2 antibody
    • Serpin peptidase inhibitor clade F antibody
    • Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibody
    • SERPINF2 antibody
    see all

References for Anti-Alpha 2 Antiplasmin antibody (ab48591)

This product has been referenced in:
  • Caillot F  et al. Novel serum markers of fibrosis progression for the follow-up of hepatitis C virus-infected patients. Am J Pathol 175:46-53 (2009). Sandwich ELISA ; Human . Read more (PubMed: 19477948) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"