Recombinant
RabMAb

Anti-alpha 2 Catenin antibody [EPR1795] (ab76015)

Overview

  • Product name
    Anti-alpha 2 Catenin antibody [EPR1795]
    See all alpha 2 Catenin primary antibodies
  • Description
    Rabbit monoclonal [EPR1795] to alpha 2 Catenin
  • Tested applications
    Suitable for: WB, IP, ICCmore details
    Unsuitable for: Flow Cyt or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in human alpha 2 Catenin.

  • Positive control
    • Mouse brain lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab76015 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 105 kDa.
IP 1/50.
ICC 1/50.
  • Application notes
    Is unsuitable for Flow Cyt or IHC-P.
  • Target

    • Function
      May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.
    • Sequence similarities
      Belongs to the vinculin/alpha-catenin family.
    • Cellular localization
      Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > adherens junction. Cell membrane. Cell projection > axon. Recruited to the nucleus upon ZNF639 overexpression.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha catenin related protein antibody
      • Alpha N catenin antibody
      • Alpha N-catenin antibody
      • Alpha-catenin-related protein antibody
      • Cadherin associated protein related antibody
      • Cancer/testis antigen 114 antibody
      • CAP R antibody
      • CAPR antibody
      • Catenin (cadherin associated protein) alpha 2 antibody
      • Catenin alpha 2 antibody
      • Catenin alpha-2 antibody
      • CT114 antibody
      • CTNA2_HUMAN antibody
      • CTNN A2 antibody
      • CTNNA 2 antibody
      • CTNNA2 antibody
      • CTNR antibody
      • DKFZp686H02198 antibody
      see all

    Images

    • Anti-alpha 2 Catenin antibody [EPR1795] (ab76015) at 1/2000 dilution + mouse brain lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 105 kDa
      Observed band size : 102 kDa (why is the actual band size different from the predicted?)

    References

    This product has been referenced in:
    • Paul C & Robaire B Impaired function of the blood-testis barrier during aging is preceded by a decline in cell adhesion proteins and GTPases. PLoS One 8:e84354 (2013). WB ; Rat . Read more (PubMed: 24391944) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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