Anti-alpha 2 Glycine Receptor antibody (ab107292)

Overview

  • Product nameAnti-alpha 2 Glycine Receptor antibody
    See all alpha 2 Glycine Receptor primary antibodies
  • Description
    Rabbit polyclonal to alpha 2 Glycine Receptor
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 335-364 of Human alpha 2 Glycine Receptor (NP_001165413.1, NP_001112358.1, NP_002054.1,NP_001112357.1)

  • Positive control
    • K562 cell line lysate; Human brain tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab107292 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab107292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 52 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionThe glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA2 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GLR antibody
    • Glra2 antibody
    • GLRA2_HUMAN antibody
    • Glycine receptor alpha 2 polypeptide antibody
    • Glycine receptor alpha 2 subunit antibody
    • Glycine receptor subunit alpha 2 antibody
    • Glycine receptor subunit alpha-2 antibody
    • Gycine receptor alpha 2 antibody
    see all

Anti-alpha 2 Glycine Receptor antibody images

  • Anti-alpha 2 Glycine Receptor antibody (ab107292) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 52 kDa
  • ab107292, at 1/50 dilution, staining alpha 2 Glycine Receptor in formalin-fixed, paraffin-embedded Human brain tissue by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.

References for Anti-alpha 2 Glycine Receptor antibody (ab107292)

ab107292 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"