Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 335-364 of Human alpha 2 Glycine Receptor (NP_001165413.1, NP_001112358.1, NP_002054.1,NP_001112357.1)
K562 cell line lysate; Human brain tissue
Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
FunctionThe glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA2 sub-subfamily.
ab107292, at 1/50 dilution, staining alpha 2 Glycine Receptor in formalin-fixed, paraffin-embedded Human brain tissue by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.
References for Anti-alpha 2 Glycine Receptor antibody (ab107292)
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