alpha 2a Adrenergic Receptor peptide (ab82446)

Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      FGYCNSSLNPVIYTIFNH

Specifications

Our Abpromise guarantee covers the use of ab82446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

    Western blot

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

  • Form
    Liquid
  • Additional notes
    This product has been dissolved by DMF
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • ADA2A_HUMAN
    • ADRA2
    • ADRA2A
    • ADRA2R
    • ADRAR
    • Adrenergic alpha 2A receptor
    • Alpha 2 adrenergic receptor subtype C10
    • Alpha 2A adrenergic receptor
    • Alpha 2AAR subtype C10
    • Alpha-2 adrenergic receptor subtype C10
    • alpha-2-adrenergic receptor, platelet type
    • Alpha-2A adrenergic receptor
    • Alpha-2A adrenoceptor
    • Alpha-2A adrenoreceptor
    • Alpha-2AAR
    • ALPHA2AAR
    • OTTHUMP00000058849
    • ZNF32
    see all
  • Function
    Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • Image 1: anti-ADRA2 (1 µg/ml)
    Image 2: anti-ADRA2 (1 µg/ml) + ab82446 (10 µg/ml)
    Image 3: anti-ADRA2 (1 µg/ml) + ab82446 (1 µg/ml)
    Image 4: anti-ADRA2 (1 µg/ml) + ab82446 (0.1 µg/ml)

References

ab82446 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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