Anti-alpha 2b Adrenergic Receptor antibody (ab91468)

Overview

  • Product nameAnti-alpha 2b Adrenergic Receptor antibody
    See all alpha 2b Adrenergic Receptor primary antibodies
  • Description
    Rabbit polyclonal to alpha 2b Adrenergic Receptor
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the center region of Human alpha 2b Adrenergic Receptor conjugated to KLH (NP_000673.2).

  • Positive control
    • MDA-MB231 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceAlpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
    • Cellular localizationCell Membrane
    • Database links
    • Alternative names
      • ADRA2B antibody
      • ADRA2RL1 antibody
      • ADRARL1 antibody
      • Alpha 2 adrenergic receptor subtype C2 antibody
      • Alpha 2B adrenoceptor antibody
      • Alpha 2B adrenoreceptor antibody
      • alpha 2BAR antibody
      • ALPHA2BAR antibody
      see all

    Anti-alpha 2b Adrenergic Receptor antibody images

    • Anti-alpha 2b Adrenergic Receptor antibody (ab91468) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

      Predicted band size : 50 kDa

    References for Anti-alpha 2b Adrenergic Receptor antibody (ab91468)

    ab91468 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"