Use at an assay dependent concentration. Predicted molecular weight: 20 kDa.
RelevanceAlpha 2 microglobulin is part of the lipocalin family. There are many different isoforms which exhibit extensive homology. It is a major urinary protein in male rats and is synthesised and secreted by hepatic parenchymal cells. Alpha 2 microglobulin is also known as MUP (major urinary protein) and is a very important allergen because it constitutes approximately 30% of the total protein content excreted in the urine. Rats are the most frequently used laboratory animals and allergy to them constitutes an occupational disease. Approximately 20 % of the personal engaged in work with laboratory animals have acquired symptoms of allergy.