alpha Fetoprotein Human ELISA Kit (ab108631)
- Product namealpha Fetoprotein Human ELISA KitSee all alpha Fetoprotein kits ...
- Detection methodColorimetric
- Tests1 x 96 well plate
- Sample typeSerum
- Assay typeSandwich
- Sensitivity= 2 ng/ml
- Range2 ng/ml - 300 ng/ml
- Assay durationMultiple steps standard assay
- Species reactivityReacts with: Human
- Product overview
ab108631 is for the quantitative determination of alpha Fetoprotein (AFP) concentration in human serum.
Alpha fetoprotein (AFP) is a glycoprotein with a molecular weight of approximately 70,000 daltons. AFP is normally produced during fetal and neonatal development by the liver, yolk sac, and in small concentrations by the gastrointestinal tract. After birth, serum AFP concentrations decrease rapidly, and by the second year of life and thereafter only trace amounts are normally detected in serum.
Elevation of serum AFP to abnormally high values occurs in several malignant diseases, most notably nonseminomatous testicular cancer and primary hepatocellular carcinoma. In the case of nonseminomatous testicular cancer, a direct relationship has been observed between the incidence of elevated AFP levels and the stage of disease. Elevated AFP levels have also been observed in samples with seminoma with nonseminomatous elements, but not in samples with pure seminoma. Therefore, AFP measurements are not recommended for use as a screening procedure to detect the presence of cancer in the general population.
- Tested applicationsSandwich ELISA more details
- Storage instructionsStore at +4°C. Please refer to protocols.
Components 1 x 96 tests Buffer 1 x 13ml Enzyme Conjugate Reagent 1 x 18ml Microtiter Plate 1 unit Set of α Fetoprotein Standards 6 vials Stop Solution 1 x 11ml TMB Reagent 1 x 11ml
- Research Areas
- AFPAlpha 1 fetoproteinAlpha fetoglobulin
Our Abpromise guarantee covers the use of ab108631 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
References for alpha Fetoprotein Human ELISA Kit (ab108631)
ab108631 has not yet been referenced specifically in any publications.