Anti-alpha Adducin (phospho T445) antibody (ab58485)

Overview

  • Product nameAnti-alpha Adducin (phospho T445) antibody
    See all alpha Adducin primary antibodies
  • Description
    Rabbit polyclonal to alpha Adducin (phospho T445)
  • Specificityab58485 detects endogenous levels of Adducin only when phosphorylated at threonine 445.
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human alpha Adducin.

  • Positive control
    • Human breast carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab58485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/5000.

Target

  • FunctionMembrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
  • Tissue specificityExpressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.
  • Sequence similaritiesBelongs to the aldolase class II family. Adducin subfamily.
  • DomainEach subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.
  • Cellular localizationCytoplasm > cytoskeleton. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADD A antibody
    • ADD1 antibody
    • ADDA antibody
    • ADDA_HUMAN antibody
    • Adducin 1 (alpha) antibody
    • Alpha adducin antibody
    • Alpha-adducin antibody
    • Erythrocyte adducin alpha subunit antibody
    • Erythrocyte adducin subunit alpha antibody
    • MGC3339 antibody
    • MGC44427 antibody
    • OTTHUMP00000151163 antibody
    • OTTHUMP00000151164 antibody
    • OTTHUMP00000151165 antibody
    • OTTHUMP00000218664 antibody
    • OTTHUMP00000218665 antibody
    see all

Anti-alpha Adducin (phospho T445) antibody images

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58485 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

References for Anti-alpha Adducin (phospho T445) antibody (ab58485)

ab58485 has not yet been referenced specifically in any publications.

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