Anti-Alpha B Crystallin antibody (ab116563)

Overview

  • Product nameAnti-Alpha B Crystallin antibody
    See all Alpha B Crystallin primary antibodies
  • Description
    Rabbit polyclonal to Alpha B Crystallin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 83-112 of Human Alpha B Crystallin (NP_001876.1).

  • Positive control
    • 293 cell (transiently transfected with the CRYAB gene) lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116563 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 20 kDa.

Target

  • FunctionMay contribute to the transparency and refractive index of the lens.
  • Tissue specificityLens as well as other tissues.
  • Involvement in diseaseDefects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
  • Sequence similaritiesBelongs to the small heat shock protein (HSP20) family.
  • Cellular localizationCytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • Information by UniProt
  • Database links
  • Alternative names
    • AACRYA antibody
    • Alpha B crystallin antibody
    • Alpha crystallin B chain antibody
    • Alpha(B)-crystallin antibody
    • Alpha-crystallin B chain antibody
    • CRYA2 antibody
    • Cryab antibody
    • CRYAB_HUMAN antibody
    • Crystallin alpha B antibody
    • Crystallin alpha polypeptide 2 antibody
    • CTPP2 antibody
    • Heat shock 20 kD like protein antibody
    • Heat shock protein beta 5 antibody
    • Heat shock protein beta-5 antibody
    • HspB5 antibody
    • Renal carcinoma antigen NY REN 27 antibody
    • Renal carcinoma antigen NY-REN-27 antibody
    • Rosenthal fiber component antibody
    see all

Anti-Alpha B Crystallin antibody images

  • All lanes : Anti-Alpha B Crystallin antibody (ab116563) at 1/100 dilution

    Lane 1 : 293 cell lysate
    Lane 2 : 293 cell (transiently transfected with the CRYAB gene) lysate

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 20 kDa

References for Anti-Alpha B Crystallin antibody (ab116563)

ab116563 has not yet been referenced specifically in any publications.

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