Overview

  • Product name
    Anti-alpha Internexin antibody
    See all alpha Internexin primary antibodies
  • Description
    Chicken polyclonal to alpha Internexin
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cat, Human
  • Immunogen

    Recombinant full length protein expressed in E. coli.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 10mM Sodium Azide.
  • Concentration information loading...
  • Purification notes
    This antibody was purified from egg yolk by chloroform delipidation followed by PEG precipitation.
  • Clonality
    Polyclonal
  • Isotype
    IgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC/IF
  • Application notes
    IF: 1/1000 and higher.
    WB: 1/10000 and higher. Detects a band of approximately 66-68 kDa (the human protein runs at ~68 kDa, while rat, mouse and other species run at ~66 kDa). Minor bands at ~150 kDa are probably covalent dimers, and bands at ~50 kDa represent alpha internexin breakdown products. (Predicted molecular weight: 55 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
    • Tissue specificity
      Found predominantly in adult CNS.
    • Sequence similarities
      Belongs to the intermediate filament family.
    • Developmental stage
      Expressed in brain as early as the 16th week of gestation, and increased rapidly and reached a steady state level by the 18th week of gestation.
    • Post-translational
      modifications
      O-glycosylated.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • Database links
    • Alternative names
      • 66 kDa neurofilament protein antibody
      • AINX_HUMAN antibody
      • Alpha Inx antibody
      • Alpha-internexin antibody
      • Alpha-Inx antibody
      • INA antibody
      • Internexin neuronal intermediate filament protein alpha antibody
      • MGC12702 antibody
      • NEF 5 antibody
      • NEF5 antibody
      • Neurofilament 5 (66kD) antibody
      • Neurofilament 5 antibody
      • Neurofilament 66 antibody
      • Neurofilament 66 tax binding protein antibody
      • Neurofilament-66 antibody
      • NF 66 antibody
      • NF-66 antibody
      • NF66 antibody
      • TXBP 1 antibody
      • TXBP1 antibody
      see all

    References for Anti-alpha Internexin antibody (ab24523)

    ab24523 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab24523.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up