Overview

  • Product name
    Anti-alpha Internexin antibody
    See all alpha Internexin primary antibodies
  • Description
    Chicken polyclonal to alpha Internexin
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cat, Human
  • Immunogen

    Recombinant full length protein expressed in E. coli.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 10mM Sodium Azide.
  • Concentration information loading...
  • Purification notes
    This antibody was purified from egg yolk by chloroform delipidation followed by PEG precipitation.
  • Clonality
    Polyclonal
  • Isotype
    IgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC/IF
  • Application notes
    IF: 1/1000 and higher.
    WB: 1/10000 and higher. Detects a band of approximately 66-68 kDa (the human protein runs at ~68 kDa, while rat, mouse and other species run at ~66 kDa). Minor bands at ~150 kDa are probably covalent dimers, and bands at ~50 kDa represent alpha internexin breakdown products. (Predicted molecular weight: 55 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
    • Tissue specificity
      Found predominantly in adult CNS.
    • Sequence similarities
      Belongs to the intermediate filament family.
    • Developmental stage
      Expressed in brain as early as the 16th week of gestation, and increased rapidly and reached a steady state level by the 18th week of gestation.
    • Post-translational
      modifications
      O-glycosylated.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • Database links
    • Alternative names
      • 66 kDa neurofilament protein antibody
      • AINX_HUMAN antibody
      • Alpha Inx antibody
      • Alpha-internexin antibody
      • Alpha-Inx antibody
      • INA antibody
      • Internexin neuronal intermediate filament protein alpha antibody
      • MGC12702 antibody
      • NEF 5 antibody
      • NEF5 antibody
      • Neurofilament 5 (66kD) antibody
      • Neurofilament 5 antibody
      • Neurofilament 66 antibody
      • Neurofilament 66 tax binding protein antibody
      • Neurofilament-66 antibody
      • NF 66 antibody
      • NF-66 antibody
      • NF66 antibody
      • TXBP 1 antibody
      • TXBP1 antibody
      see all

    References

    ab24523 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab24523.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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