Overview

  • Product nameAnti-alpha MSH antibody
    See all alpha MSH primary antibodies
  • Description
    Rabbit polyclonal to alpha MSH
  • SpecificityAnti-a-MSH cross-reacts with des-Ac-a-MSH and [Val-OH13]-a-MSH. Minimal cross-reactivity is observed with human ACTH (1-39) and ACTH (1-24).
  • Tested applicationsSuitable for: RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic human MSH alpha peptide conjugated to bovine serum albumin. The mid-region sequence of MSH alpha (amino acids 4-10) is identical to the ACTH and MSH beta sequences and highly conserved in the MSH gamma sequence.

  • General notesAffinity constant Ka: at least 1x109 L/M

Properties

Applications

Our Abpromise guarantee covers the use of ab50013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA
  • Application notesRIA: 1/3000 (2nd antibody and polyethylene glycol method) using 5-7pg of 125I-a-MSH.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceMelanocyte-stimulating hormone belongs to a group called the melanocortins. This group includes ACTH, alpha-MSH, beta-MSH and gamma-MSH; these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). Alpha-MSH is the most important melanocortin for pigmentation. It increases the pigmentation of skin by increasing melanin production in melanocytes.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Alpha MSH antibody
      • Melanotropin alpha antibody
      • POMC antibody
      • proopiomelanocortin antibody

    References for Anti-alpha MSH antibody (ab50013)

    ab50013 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab50013.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"