• Product nameAnti-alpha Sarcoglycan antibody
    See all alpha Sarcoglycan primary antibodies
  • Description
    Rabbit polyclonal to alpha Sarcoglycan
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human alpha Sarcoglycan.

  • Positive control
    • Jurkat, HepG2 and HeLa cell extracts.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab92522 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab92522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 43 kDa.


  • FunctionComponent of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • Tissue specificityMost strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
  • Involvement in diseaseDefects in SGCA are the cause of limb-girdle muscular dystrophy type 2D (LGMD2D) [MIM:608099]; also known as Duchenne-like muscular dystrophy autosomal recessive type 2 or severe childhood autosomal recessive muscular dystrophy (SCARMD). LGMD2D is an autosomal recessive degenerative myopathy characterized by progressive muscle wasting from early childhood with loss of independent ambulation by teenage years. Muscle biopsy shows necrosis, decreased immunostaining for alpha sarcoglycan, and adhalin deficiency. The phenotype is less severe than LGMD2C.
  • Sequence similaritiesBelongs to the sarcoglycan alpha/epsilon family.
  • Cellular localizationCell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 50 DAG antibody
    • 50 kDa dystrophin associated glycoprotein antibody
    • 50 kDa dystrophin-associated glycoprotein antibody
    • 50DAG antibody
    • 50kD DAG antibody
    • 59kDa antibody
    • A2 antibody
    • adhalin antibody
    • ADL antibody
    • Alpha SG antibody
    • Alpha-sarcoglycan antibody
    • Alpha-SG antibody
    • Asg antibody
    • DAG2 antibody
    • DMDA2 antibody
    • Dystroglycan 2 antibody
    • Dystroglycan-2 antibody
    • LGMD2D antibody
    • sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody
    • SCARMD1 antibody
    • Sgca antibody
    • SGCA_HUMAN antibody
    see all

Anti-alpha Sarcoglycan antibody images

  • All lanes : Anti-alpha Sarcoglycan antibody (ab92522) at 1/500 dilution

    Lane 1 : Jurkat cell extracts
    Lane 2 : HepG2 cell extracts
    Lane 3 : HeLa cell extracts
    Lane 4 : HeLa cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 43 kDa

References for Anti-alpha Sarcoglycan antibody (ab92522)

ab92522 has not yet been referenced specifically in any publications.

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