You have changed your country from to
. Please be aware that this will change the currency in the purchasing process.
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »This product is covered by the Abpromise guarantee. Our scientific support team are available to answer any questions or queries - fill out an inquiry form for ab40863 for help.
Alternatively, you can search the previous enquiries about this product to see if your query has already been answered.
|
|||||||||
 | |||||||||
|
|||||||||
Dear Sir/ Madam, For my study, I want to do immunohistochemistry on paraffin embedded coupes which contain both human and mouse tissue and I want to distinguish between these both. Therefore, I need specific anti-mouse antibodies for the proteins I am interested in. Two of these proteins are alpha-SMA and VIP. I kindly ask you if you can give me some more information about these antibodies (AB40863 and AB43841), especially about cross-reactivity and if it can be used for IHC-P. And, if possible, can you give me a quote for these antibodies as well? Thanks in advance! Yours sincerely, |
|||||||||
ANSWER: |
Thank you very much for your inquiry. Unfortunately, we do not have any antibodies against SMA and VIP that do NOT react with human. When a species is not stated as "reacts with" it is simply not tested yet, but could well be recognised by the antibody. For your purposes I suggest to only use antibodies where it is clearly stated "does NOT react with". I attached a excel file with all our antibodies that do not react with human but do with mouse. I hope this will help. Please do not hesitate to contact me again with any further questions. |
||||||||
|
|||||||||
How was non-reactivity with cytoplasmic gamma and beta actin determined? |
|||||||||
ANSWER: |
Thank you for your enquiry. The production and characterization of this clone, B4, is described in the following reference: Lessard, JL. 'Two monoclonal antibodies to actin: one muscle selective and one generally reactive.' Cell Motil Cytoskeleton. 1988;10(3):349-62. PMID: 2460261 I hope this information helps. Please do not hesitate to contact us if you need any more advice or information. |
||||||||
|
|||||||||
| |||||||||
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
![Immunocytochemistry/ Immunofluorescence - alpha smooth muscle Actin antibody [B4] (ab40863)](/ps/datasheet/Images/40/ab40863/40863.jpg)