Anti-Alpha-synuclein (phospho S129) antibody (ab59264)

Publishing research using ab59264? Please let us know so that we can cite the reference in this datasheet.

ab59264 has been referenced in 25 publications.

  • Svarcbahs R  et al. Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo. Sci Rep 8:1552 (2018). PubMed: 29367610
  • Gerson JE  et al. Tau oligomers mediate a-synuclein toxicity and can be targeted by immunotherapy. Mol Neurodegener 13:13 (2018). PubMed: 29544548
  • Bido S  et al. Mitochondrial division inhibitor-1 is neuroprotective in the A53T-a-synuclein rat model of Parkinson's disease. Sci Rep 7:7495 (2017). PubMed: 28790323
  • Bobela W  et al. Modulating the catalytic activity of AMPK has neuroprotective effects against a-synuclein toxicity. Mol Neurodegener 12:80 (2017). IF . PubMed: 29100525
  • Watanabe Y  et al. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy 13:133-148 (2017). PubMed: 27846364
  • Zha J  et al. A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses. Sci Rep 6:36631 (2016). PubMed: 27824125
  • Niu Y  et al. Early Parkinson's disease symptoms in a-synuclein transgenic monkeys. Hum Mol Genet 24:2308-17 (2015). PubMed: 25552648
  • Ambrosi G  et al. Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease. Biochim Biophys Acta 1842:1385-94 (2014). PubMed: 24854107
  • Aulic S  et al. Defined a-synuclein prion-like molecular assemblies spreading in cell culture. BMC Neurosci 15:69 (2014). ICC/IF ; Human . PubMed: 24898419
  • Aldrin-Kirk P  et al. Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons. PLoS One 9:e100869 (2014). IHC-Fr ; Mouse . PubMed: 24999658
  • Bae EJ  et al. Glucocerebrosidase depletion enhances cell-to-cell transmission of a-synuclein. Nat Commun 5:4755 (2014). PubMed: 25156829
  • Miners JS  et al. Accumulation of a-synuclein in dementia with Lewy bodies is associated with decline in the a-synuclein-degrading enzymes kallikrein-6 and calpain-1. Acta Neuropathol Commun 2:164 (2014). IHC-P ; Human . PubMed: 25476568
  • Buehl CJ  et al. Resolving acetylated and phosphorylated proteins by neutral urea Triton-polyacrylamide gel electrophoresis: NUT-PAGE. Biotechniques 57:72-80 (2014). PubMed: 25109292
  • Bétemps D  et al. Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological a-synuclein by enhanced ELISA. Acta Neuropathol Commun 2:29 (2014). WB, ELISA . PubMed: 24624994
  • Henderson-Smith A  et al. SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening. PLoS One 8:e77711 (2013). WB . PubMed: 24204929
  • Kiely AP  et al. a-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta Neuropathol 125:753-69 (2013). ICC/IF ; Human . PubMed: 23404372
  • Janezic S  et al. Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. Proc Natl Acad Sci U S A 110:E4016-25 (2013). Mouse . PubMed: 24082145
  • Ling H  et al. TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT. Neurobiol Aging 34:2889.e5-9 (2013). IHC-Fr ; Human . PubMed: 23664753
  • Chesselet MF  et al. A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice. Neurotherapeutics 9:297-314 (2012). PubMed: 22350713
  • Lastres-Becker I  et al. a-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease. Hum Mol Genet 21:3173-92 (2012). ICC/IF ; Mouse . PubMed: 22513881
  • Nakata Y  et al. Accumulation of a-synuclein triggered by presynaptic dysfunction. J Neurosci 32:17186-96 (2012). PubMed: 23197711
  • Gan L  et al. Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model. J Neurosci 32:17775-87 (2012). Mouse . PubMed: 23223297
  • Fiske M  et al. Contribution of Alanine-76 and Serine Phosphorylation in a-Synuclein Membrane Association and Aggregation in Yeasts. Parkinsons Dis 2011:392180 (2011). WB ; Human . PubMed: 21826257
  • Fiske M  et al. Familial Parkinson's Disease Mutant E46K a-Synuclein Localizes to Membranous Structures, Forms Aggregates, and Induces Toxicity in Yeast Models. ISRN Neurol 2011:521847 (2011). PubMed: 22389823
  • Pan-Montojo F  et al. Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. PLoS One 5:e8762 (2010). IHC-FoFr ; Mouse . PubMed: 20098733


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