Overview

  • Product nameAnti-ALS2CR2 antibody
    See all ALS2CR2 primary antibodies
  • Description
    Goat polyclonal to ALS2CR2
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    CDFPDEKDSYWEF

    , corresponding to C terminal amino acids 406-418 of Human ALS2CR2 (NP_061041.2).

  • Positive control
    • Human Heart tissue; Human heart lysate and HEK293 lysate overexpressing ALS2CR2.

Properties

Applications

Our Abpromise guarantee covers the use of ab117421 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 47 kDa.
ELISA 1/32000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionPseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
  • Tissue specificityHighly expressed in heart, skeletal muscle, testis, liver and colon.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • DomainThe protein kinase domain is predicted to be catalytically inactive.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALS2 chromosome region gene 2 antibody
    • ALS2CR2 antibody
    • Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2 antibody
    • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein antibody
    • CALS 21 antibody
    • CALS-21 antibody
    • ILP interacting protein ILPIPA antibody
    • ILP-interacting protein antibody
    • ILPIP antibody
    • ILPIPA antibody
    • Likely ortholog of mouse polyploidy associated protein kinase antibody
    • PAPK antibody
    • PRO1038 antibody
    • Pseudokinase ALS2CR2 antibody
    • STE20-related kinase adapter protein beta antibody
    • STRAB_HUMAN antibody
    • STRAD beta antibody
    • STRADB antibody
    see all

Anti-ALS2CR2 antibody images

  • ab117421, at 3.75 ug/ml, staining ALS2CR2 in Formalin-fixed, Paraffin-embedded Human Heart tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-ALS2CR2 antibody (ab117421) at 1 µg/ml + Human heart lysate in RIPA buffer at 30 µg
    Developed using the ECL technique

    Predicted band size : 47 kDa
  • All lanes : Anti-ALS2CR2 antibody (ab117421) at 3 µg/ml

    Lane 1 : HEK293 lysate (mock transfection)
    Lane 2 : HEK293 lysate (overexpressing ALS2CR2)


    Predicted band size : 47 kDa

References for Anti-ALS2CR2 antibody (ab117421)

ab117421 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"