This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

  • Product name
  • Description
    Goat polyclonal to ALS2CR3

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Species reactivity

    Predicted to work with: Human
  • Immunogen

    Synthetic peptide:

    CTSSPKMGVLKED

    , corresponding to C terminal amino acids 902-914 of Human ALS2CR3.

  • General notes
    GenBank Accession Number – NP_055864 LocusLink ID - 66008 (human) Gene Ontology terms - intracellular transporter activity; receptor binding; kinesin complex; cytoplasm; plasma membrane; neurotransmitter transport.

Properties

Applications

  • Application notes
    ELISA: peptide ELISA (antibody detection limit dilution >1/32000).
    Western blot: No signals obtained yet but low background observed in Human Heart and Human Brain extracts.
  • Target

    • Function
      May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
    • Tissue specificity
      Widely expressed, with highest expression in heart.
    • Sequence similarities
      Contains 1 HAP1 N-terminal domain.
    • Post-translational
      modifications
      O-glycosylated.
    • Cellular localization
      Cytoplasm. Early endosome. Mitochondrion. Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner.
    • Information by UniProt
    • Database links
    • Alternative names
      • ALS2CR 3 antibody
      • Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3 antibody
      • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein antibody
      • CALS C antibody
      • GRIF 1 antibody
      • GRIF1 antibody
      • KIAA0549 antibody
      • OIP98 antibody
      • Trafficking kinesin-binding protein 2 antibody
      • Trafficking protein kinesin binding 2 antibody
      • Trak2 antibody
      • TRAK2_HUMAN antibody
      see all

    References

    ab4200 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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