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Products:Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Overview
Product name
Anti-AMACR antibody
See all AMACR products (9) ...
Description
Rabbit polyclonal to AMACR
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide (Human)
Positive control
Prostate carcinoma.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 1% BSA
Concentration
Concentration information loading...
Purity
IgG fraction
Purification notes
Purified immunoglobulin fraction of rabbit antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Proto-oncogenes
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Applications
Show applications key
Our Abpromise guarantee covers the use of ab12498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P
Application notes
IHC-P: 1/25 - 1/50. Perform heat mediated antigen retrieval with 10 mM citrate buffer, pH 6.0 before commencing with IHC staining protocol. We suggest an incubation period of 30 minutes at room temperature.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMARC protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
Cellular localization
Mitochondrial, Peroxisome
Alternative names
- 2 arylpropionyl CoA epimerase antibody
- 2 methylacyl CoA racemase antibody
- Alpha methylacyl CoA racemase antibody
see all
Database links
- Entrez Gene: 23600 Human
- Omim: 604489 Human
- SwissProt: Q9UHK6 Human
References for Anti-AMACR antibody (ab12498)
ab12498 has not yet been referenced specifically in any publications.
Publishing research using ab12498? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"