Overview

  • Product nameAMD 3465 hexahydrobromide
  • Description
    Potent and selective CXCR4 antagonist
  • Biological descriptionPotent and selective CXCR4 antagonist. Shows 8-fold greater affinity than AMD 3100 (ab120718). Potent HIV entry inhibitor (IC50 = ~10 nM). Additionally mobilizes stem cells in vivo.
  • Purity> 97%

Properties

  • Chemical nameN-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
  • Molecular weight896.08
  • Chemical structureChemical Structure
  • Molecular formulaC24H38N6.6HBr
  • CAS Number185991-07-5
  • PubChem identifier483559
  • Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in water to 50 mM and in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESBr.Br.Br.Br.Br.Br.C3NCCCNCCN(Cc2ccc(CNCc1ccccn1)cc2)CCCNC3
  • Source

    Synthetic

    References for AMD 3465 hexahydrobromide (ab120809)

    ab120809 has not yet been referenced specifically in any publications.

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