Overview

  • Product name
    AMD 3465 hexahydrobromide
  • Description
    Potent and selective CXCR4 antagonist
  • Biological description
    Potent and selective CXCR4 antagonist. Shows 8-fold greater affinity than AMD 3100 (ab120718). Potent HIV entry inhibitor (IC50 = ~10 nM). Additionally mobilizes stem cells in vivo.
  • Purity
    > 97%

Properties

  • Chemical name
    N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
  • Molecular weight
    896.08
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C24H38N6.6HBr
  • CAS Number
    185991-07-5
  • PubChem identifier
    483559
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 50 mM and in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    Br.Br.Br.Br.Br.Br.C3NCCCNCCN(Cc2ccc(CNCc1ccccn1)cc2)CCCNC3
  • Source

    Synthetic

    References for AMD 3465 hexahydrobromide (ab120809)

    ab120809 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab120809.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

    Sign up