Overview

  • Product name
    Anti-AMH antibody [5/6]
    See all AMH primary antibodies
  • Description
    Mouse monoclonal [5/6] to AMH
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Sheep, Human, Baboon
    Predicted to work with: Rat, Cow, Pig
  • Immunogen

    Synthetic peptide:

    VPTAYAGKLLISLSEERISAHHVPNMVATEC

    , corresponding to C terminal amino acids 527-557 of Human AMH.

  • Positive control
    • Mouse ovary tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab24542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/40. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • Anti muellerian hormone antibody
    • MIF antibody
    • MIS antibody
    • Muellerian inhibiting factor antibody
    • Mullerian inhibiting substance antibody
    see all

Images

  • Ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.

References

This product has been referenced in:
  • Satie AP  et al. Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility. J Biol Chem 286:23280-95 (2011). IHC-P ; Mouse . Read more (PubMed: 21515676) »
  • Kevenaar ME  et al. Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice. Endocrinology 147:3228-34 (2006). Read more (PubMed: 16556768) »

See all 4 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab24542.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up