Anti-Amino-terminal enhancer of split antibody (ab62556)


  • Product nameAnti-Amino-terminal enhancer of split antibody
    See all Amino-terminal enhancer of split primary antibodies
  • Description
    Rabbit polyclonal to Amino-terminal enhancer of split
  • Tested applicationsSuitable for: ICC, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    16 amino acid synthetic peptide from near the amino-terminus of human GRG (Groucho homologue)

  • Positive control
    • 293 cells and cell lysate.



Our Abpromise guarantee covers the use of ab62556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 10 µg/ml.
WB Use a concentration of 2 - 4 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 22 kDa).
ICC/IF Use a concentration of 20 µg/ml.


  • FunctionTranscriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
  • Tissue specificityFound predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.
  • Sequence similaritiesBelongs to the WD repeat Groucho/TLE family.
  • DomainLacks the C-terminal WD repeats.
  • Post-translational
    Ubiquitinated by XIAP/BIRC4.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Aes 1 antibody
    • Aes 2 antibody
    • aes antibody
    • AES_HUMAN antibody
    • Aes1 antibody
    • Aes2 antibody
    • Amino enhancer of split antibody
    • Amino terminal enhancer of split antibody
    • Amino-terminal enhancer of split antibody
    • Esp 1 antibody
    • Esp1 antibody
    • Gp130 associated protein GAM antibody
    • Gp130-associated protein GAM antibody
    • GRG 5 antibody
    • GRG antibody
    • GRG protein antibody
    • Grg-5 antibody
    • GRG5 antibody
    • Groucho-related protein 5 antibody
    • Protein ESP 1 antibody
    • Protein ESP1 antibody
    • Protein GRG antibody
    • TLE 5 antibody
    • TLE5 antibody
    see all

Anti-Amino-terminal enhancer of split antibody images

  • Lane 1 : Anti-Amino-terminal enhancer of split antibody (ab62556) at 2 µg/ml
    Lane 2 : Anti-Amino-terminal enhancer of split antibody (ab62556) at 4 µg/ml

    Lane 1 : 293 cell lysate
    Lane 2 : 293 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size : 22 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 24 kDa (possible isoform).
  • ab62556 at 10µg/ml staining GRG (Groucho homologue) in 293 cells by Immunocytochemistry.
  • Immunofluorescence of AES in 293 cells using ab62556 at 20 ug/ml.

References for Anti-Amino-terminal enhancer of split antibody (ab62556)

ab62556 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab62556.
Please use the links above to contact us or submit feedback about this product.