Overview

  • Product name
    Amlexanox
  • Description
    Selective TBK1 and IKKε inhibitor
  • Biological description
    Selective TBK1 and IKKε inhibitor (IC50 = 1-2 μM). Shows antiallergic, antiobesogenic and anti-inflammatory effects in vivo. Orally active.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Reilly SM  et al. An inhibitor of the protein kinases TBK1 and IKK-? improves obesity-related metabolic dysfunctions in mice. Nat Med 19:313-21 (2013). Read more (PubMed: 23396211) »
  • Halder SK  et al. Neuron-specific non-classical release of prothymosin alpha: a novel neuroprotective damage-associated molecular patterns. J Neurochem 123:262-75 (2012). Read more (PubMed: 22853710) »
  • Gonzalez-Hilarion S  et al. Rescue of nonsense mutations by amlexanox in human cells. Orphanet J Rare Dis 7:58 (2012). Read more (PubMed: 22938201) »

See 0 Publications for this product

Customer reviews and Q&As

The formulation of item ab142825, Amlexanox, is suitable for administration to mice.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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