Overview

  • Product name
  • Description
    Rabbit polyclonal to AMPD1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human, Chimpanzee, Monkey, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 500-550 of Human AMPD1

  • Positive control
    • Skeletal muscle tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab78045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 87 kDa.
IHC-P Use a concentration of 5 - 10 µg/ml.

Target

  • Relevance
    AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.
  • Database links
  • Alternative names
    • Adenosine monophosphate deaminase 1 (isoform M) antibody
    • Adenosine monophosphate deaminase 1 antibody
    • AMP deaminase 1 antibody
    • AMP deaminase isoform M antibody
    • AMPD 1 antibody
    • AMPD antibody
    • Ampd01 antibody
    • MAD antibody
    • MADA antibody
    • Myoadenylate deaminase antibody
    • RATAMPD01 antibody
    • Skeletal muscle AMPD antibody
    see all

Images

  • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded skeletal muscle tissue using 10 ?g/ml ab78045.

References

ab78045 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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