Validated using a knockout cell line

Anti-AMPK alpha 1 antibody [Y365] (ab32047)

Publishing research using ab32047? Please let us know so that we can cite the reference in this datasheet.

ab32047 has been referenced in 32 publications.

  • Luo L  et al. Combination treatment of adipose-derived stem cells and adiponectin attenuates pulmonary arterial hypertension in rats by inhibiting pulmonary arterial smooth muscle cell proliferation and regulating the AMPK/BMP/Smad pathway. Int J Mol Med 41:51-60 (2018). PubMed: 29115380
  • Li Y  et al. AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction. Int J Mol Med 41:2535-2544 (2018). PubMed: 29484369
  • Chung EJ  et al. AICAR suppresses TNF-a-induced complement factor B in RPE cells. Sci Rep 7:17651 (2017). PubMed: 29247196
  • Ma D  et al. Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III. Sci Rep 7:42957 (2017). WB . PubMed: 28220885
  • Han X  et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell 15:416-27 (2016). PubMed: 26890602
  • Meng X  et al. Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5'-Monophosphate (AMP)-activated Protein Kinase a1. J Biol Chem 291:10625-34 (2016). PubMed: 27013659
  • Vigelsø A  et al. The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate intensity exercise in human skeletal muscle. J Physiol N/A:N/A (2016). PubMed: 26801521
  • Chang TJ  et al. Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation. Sci Rep 6:23403 (2016). WB ; Rat . PubMed: 26997114
  • de Oliveira WH  et al. Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice. Brain Res N/A:N/A (2016). PubMed: 27174003
  • Anandhan A  et al. Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (a-Synuclein)-Environment (Paraquat) Interactions. Mol Neurobiol N/A:N/A (2016). WB ; Mouse . PubMed: 27324791
  • Hill K  et al. Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK. J Neurosci 36:7497-510 (2016). IHC ; Mouse . PubMed: 27413159
  • Shi X  et al. Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups. J Cereb Blood Flow Metab N/A:N/A (2016). PubMed: 27381825
  • Hu XK  et al. Liraglutide attenuates the osteoblastic differentiation of MC3T3-E1 cells by modulating AMPK/mTOR signaling. Mol Med Rep 14:3662-8 (2016). PubMed: 27600753
  • Liu Z  et al. Adiponectin reduces ER stress-induced apoptosis through PPARa transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis 7:e2487 (2016). WB ; Mouse . PubMed: 27882945
  • Yan Y  et al. SUMOylation of AMPKa1 by PIAS4 specifically regulates mTORC1 signalling. Nat Commun 6:8979 (2015). IP ; Mouse . PubMed: 26616021
  • Ramiscal RR  et al. Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation. Elife 4:N/A (2015). WB, IP, IF ; Mouse . PubMed: 26496200
  • Wagschal A  et al. Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis. Nat Med 21:1290-7 (2015). PubMed: 26501192
  • Wang YG & Yang TL Liraglutide reduces fatty degeneration in hepatic cells via the AMPK/SREBP1 pathway. Exp Ther Med 10:1777-1783 (2015). WB ; Human . PubMed: 26640549
  • Zou D  et al. Protective effects of myricetin on acute hypoxia-induced exercise intolerance and mitochondrial impairments in rats. PLoS One 10:e0124727 (2015). WB ; Rat . PubMed: 25919288
  • Anandhan A  et al. Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways. Neurobiol Dis 81:76-92 (2015). WB ; Rat . PubMed: 25497688
  • Ritho J  et al. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep 12:734-42 (2015). WB ; Human . PubMed: 26212320
  • Chen K  et al. Long-term artificial selection reveals a role of TCTP in autophagy in Mammalian cells. Mol Biol Evol 31:2194-211 (2014). PubMed: 24890374
  • Rottiers V  et al. Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR. Sci Transl Med 5:212ra162 (2013). WB ; African green monkey . PubMed: 24259050
  • Srivastava S  et al. Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet. FASEB J : (2012). Mouse . PubMed: 22362892
  • Lin YY  et al. Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature 482:251-5 (2012). PubMed: 22318606
  • Hou J  et al. Liraglutide, a long-acting GLP-1 mimetic, and its metabolite attenuate inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab 32:2201-10 (2012). PubMed: 22968320
  • Eckle T  et al. Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. Nat Med 18:774-82 (2012). WB . PubMed: 22504483
  • Ju TC  et al. Nuclear translocation of AMPK-{alpha}1 potentiates striatal neurodegeneration in Huntington's disease. J Cell Biol 194:209-27 (2011). PubMed: 21768291
  • Shi T  et al. SIRT3 reduces lipid accumulation via AMPK activation in human hepatic cells. J Dig Dis 11:55-62 (2010). WB ; Human . PubMed: 20132432
  • Lee-Young RS  et al. Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo. J Biol Chem 284:23925-34 (2009). WB, IP ; Mouse . PubMed: 19525228
  • Moir H  et al. AMPK inactivation in mononuclear cells: a potential intracellular mechanism for exercise-induced immunosuppression. Appl Physiol Nutr Metab 33:75-85 (2008). WB ; Human . PubMed: 18347656
  • Sag D  et al. Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. J Immunol 181:8633-41 (2008). WB ; Human, Mouse . PubMed: 19050283


Sign up