Overview

  • Product name
  • Description
    Goat polyclonal to AMPK beta 2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide to Human PRKAB2

  • Positive control
    • Human small intestine (submucosal plexus) tissue, Human liver tissue.

Applications

Our Abpromise guarantee covers the use of ab110141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.
  • Sequence similarities
    Belongs to the 5'-AMP-activated protein kinase beta subunit family.
  • Post-translational
    modifications
    Phosphorylated when associated with the catalytic subunit.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' AMP activated protein kinase beta 2 subunit antibody
    • 5' AMP activated protein kinase subunit beta 2 antibody
    • 5''-AMP-activated protein kinase subunit beta-2 antibody
    • AAKB2_HUMAN antibody
    • AMP activated protein kinase beta 2 non catalytic subunit antibody
    • AMPK beta 2 antibody
    • AMPK beta 2 chain antibody
    • AMPK subunit beta 2 antibody
    • AMPK subunit beta-2 antibody
    • MGC61468 antibody
    • PRKAB 2 antibody
    • Prkab2 antibody
    • Protein kinase AMP activated beta 2 non catalytic subunit antibody
    see all

Images

  • ab110141, at 3.75 µg/ml, staining PRKAB2 in Human small intestine (submucosal plexus) tissue by immunohistochemistry. After incubation with ab110141, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
  • ab110141, at 3.75 µg/ml, staining PRKAB2 in Human liver tissue by immunohistochemistry. After incubation with the ab110141, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

References

ab110141 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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