Overview

  • Product nameAnti-Amylin antibody
    See all Amylin primary antibodies
  • Description
    Rabbit polyclonal to Amylin
  • SpecificitySpecific for human amylin. No significant sequence homology with other calcitonin family of peptides.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide 13aa sequence mapping to the middle region of human (KLH coupled).

Properties

Applications

Our Abpromise guarantee covers the use of ab18019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000 - 1/50000.

Target

  • FunctionSelectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
  • Sequence similaritiesBelongs to the calcitonin family.
  • DomainThe mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
  • Post-translational
    modifications
    Amyloid fibrils are degraded by IDE.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amylin antibody
    • DAP antibody
    • Diabetes associated peptide antibody
    • Diabetes-associated peptide antibody
    • IAP antibody
    • IAPP antibody
    • IAPP_HUMAN antibody
    • Insulinoma amyloid peptide antibody
    • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
    • Islet amyloid polypeptide antibody
    see all

References for Anti-Amylin antibody (ab18019)

ab18019 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I am sorry, but the precise location or the aa sequence is considered proprietary information by the laboratory. I am sorry I can't be of more assistance in this occasion. Should you require any further information, ...

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Thank you for your reply. I am still uncertain as to whether the antibody is working for you or not. As I stated in my previous email, the immunogen used to make ab18019 is a sequence that is found in both the mature (amylin) and immature (pre...

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Thank you for your enquiry. I received your fax. The issue with ab18019 is that the protein it recognizes is 10 kD if it is the full-length unprocessed precursor. Many times when the protein is being made however and moving through the ER, Golgi, ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"