Anti-Amylin antibody (ab53952)

Overview

  • Product nameAnti-Amylin antibody
    See all Amylin primary antibodies
  • Description
    Rabbit polyclonal to Amylin
  • Tested applicationsSuitable for: IP, ELISA, RIAmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Guinea pig, Cat, Dog, Human, Chinese Hamster
  • Immunogen

    Synthetic peptide:

    KCNTATCATQRLANFLVRSSNNLGP

    conjugated to KLH, corresponding to amino acids 38-62 of Rat Amylin

Properties

Applications

Our Abpromise guarantee covers the use of ab53952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • FunctionSelectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
  • Sequence similaritiesBelongs to the calcitonin family.
  • DomainThe mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
  • Post-translational
    modifications
    Amyloid fibrils are degraded by IDE.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amylin antibody
    • DAP antibody
    • Diabetes associated peptide antibody
    • Diabetes-associated peptide antibody
    • IAP antibody
    • IAPP antibody
    • IAPP_HUMAN antibody
    • Insulinoma amyloid peptide antibody
    • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
    • Islet amyloid polypeptide antibody
    see all

References for Anti-Amylin antibody (ab53952)

ab53952 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Frozen sections)
Sample Rat Tissue sections (brain)
Permeabilization No
Specification brain
Blocking step antibody diluent as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
Fixative Acetone
Username

Mr. Mehmet Sedat Feyat

Verified customer

Submitted Sep 11 2015

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (Pancreatic tissue sections)
Specification Pancreatic tissue sections
Fixative Formalin
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: 10 mM Citrate buffer pH6.0
Permeabilization No
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 21°C
Username

Abcam user community

Verified customer

Submitted Sep 06 2012

I am very pleased to hear you would like to accept our offer and test ab53952 on mouse tissue by IHC. This code will give you one free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for IHC and include this...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"