Anti-Amylin antibody, prediluted (ab15128)

Overview

  • Product nameAnti-Amylin antibody, prediluted
    See all Amylin primary antibodies
  • Description
    Rabbit polyclonal to Amylin, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal).

  • Positive control
    • Pancreas.

Properties

Applications

Our Abpromise guarantee covers the use of ab15128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min before commencing with staining protocol.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSelectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
    • Sequence similaritiesBelongs to the calcitonin family.
    • DomainThe mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
    • Post-translational
      modifications
      Amyloid fibrils are degraded by IDE.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Amylin antibody
      • DAP antibody
      • Diabetes associated peptide antibody
      • Diabetes-associated peptide antibody
      • IAP antibody
      • IAPP antibody
      • IAPP_HUMAN antibody
      • Insulinoma amyloid peptide antibody
      • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
      • Islet amyloid polypeptide antibody
      see all

    Anti-Amylin antibody, prediluted images

    • ab15128 staining Amylin in human pancreas by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections.

    References for Anti-Amylin antibody, prediluted (ab15128)

    ab15128 has not yet been referenced specifically in any publications.

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    Thank you for your enquiry and your interest in our products.
    Concerning ab18018 - there is significant sequence homology between human amylin and that of mouse and rat, but this antibody has only been tested with human samples.
    Unfortunately...

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