Anti-Amyloid A Component antibody [mcl], prediluted (ab7505)

Overview

  • Product name
    Anti-Amyloid A Component antibody [mcl], prediluted
    See all Amyloid A Component primary antibodies
  • Description
    Mouse monoclonal [mcl] to Amyloid A Component, prediluted
  • Specificity
    This antibody reacts with amyloid deposits in all organs and tissues. It reacts specifically with amyloid A protein in the native fibrils as well as fixed fibrils but does not show any reactivity with non-amyloid A fibril protein.
  • Tested applications
    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human amyloid A protein coupled to horseradish peroxidase and kininogen.

  • Positive control
    • Kidney

Properties

Applications

Our Abpromise guarantee covers the use of ab7505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notes
    IHC-P: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammatory stimuli (acute phase SAAs). These proteins are produced predominantly by the liver. The conservation of these proteins throughout invertebrates and vertebrates suggests that SAAs play a highly essential role in all animals.
    • Cellular localization
      Extracellular; Amyloid fibrils.

    References for Anti-Amyloid A Component antibody [mcl], prediluted (ab7505)

    This product has been referenced in:
    • Urieli-Shoval S  et al. Widespread expression of serum amyloid A in histologically normal human tissues. Predominant localization to the epithelium. J Histochem Cytochem 46:1377-84 (1998). Read more (PubMed: 9815279) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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