Amyloidogenic peptide forming an antiparallel β-sheet. Amyloid β peptide (16-22).
Amyloidogenic peptide forming an antiparallel β-sheet. A 7 residue section of the parent β-peptide (42 residues) from Alzheimer's amyloid precursor protein. Comprises the central hydrophobic core thought to be important in amyloid β formation. Region contains four Alzheimer's disease causing mutation sites.
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in water to 1 mg/ml
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Favrin G et al. Oligomerization of amyloid Abeta16-22 peptides using hydrogen bonds and hydrophobicity forces. Biophys J87:3657-64 (2004).
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Ma B & Nussinov R Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects. Proc Natl Acad Sci U S A99:14126-31 (2002).
Read more (PubMed: 12391326) »