Amyloid β peptide fragment. Displays cytotoxic effect on neurons. Forms aggregates and typical amyloid fibrils resembling those of the amyloid beta protein.
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in 1%NH4OH/Water to 1 mg/ml
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Sgourakis NG et al. Atomic-level characterization of the ensemble of the Aß(1-42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms. J Mol Biol405:570-83 (2011).
Read more (PubMed: 21056574) »
Zhao BQ et al. Amelioration of dementia induced by Aß 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain. Int J Pharm405:1-8 (2011).
Read more (PubMed: 21093564) »
Takadera T et al. Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention. Neurosci Lett161:41-4 (1993).
Read more (PubMed: 7504801) »