Overview

  • Product name
    Amyloid β Peptide (31-35)
  • Description
    Amyloidogenic peptide. Amyloid β Peptide (31-35).
  • Biological description

    Amyloidogenic peptide. Induces apoptosis/neurodegeneration in vitro. These effects are orchestrated by the oxidation status of methionine 35. Involves a number of signaling pathways including JNK, caspases and PKA.

  • Purity
    > 95%

Properties

References

This product has been referenced in:
  • Zhao L  et al. Amyloid beta-peptide 31-35-induced neuronal apoptosis is mediated by caspase-dependent pathways via cAMP-dependent protein kinase A activation. Aging Cell 7:47-57 (2008). Read more (PubMed: 18005252) »
  • Misiti F  et al. Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta-protein fragment (31-35) on isolated brain mitochondria. Neuroscience 126:297-303 (2004). Read more (PubMed: 15207347) »
  • Yan XZ  et al. Beta-amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons. Neuroscience 92:177-84 (1999). Read more (PubMed: 10392840) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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