Anti-Angiopoietin 1 antibody [171718] (ab49694)

Overview

  • Product nameAnti-Angiopoietin 1 antibody [171718]
    See all Angiopoietin 1 primary antibodies
  • Description
    Mouse monoclonal [171718] to Angiopoietin 1
  • SpecificityThis antibody shows no cross-reactivity with recombinant human angiopoietin-2, recombinant human angiopoietin-4, recombinant mouse angiopoietin-like 3, and recombinant human cornea-derived transcript 6 (CDT-6).
  • Tested applicationsSuitable for: Indirect ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified, recombinant, full length human Angiopoietin 1, NSO-derived

Properties

Applications

Our Abpromise guarantee covers the use of ab49694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA Use a concentration of 0.5 - 1 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 58 kDa.

Target

  • FunctionBinds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
  • Sequence similaritiesContains 1 fibrinogen C-terminal domain.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGP 1 antibody
    • AGP1 antibody
    • AGPT antibody
    • ANG 1 antibody
    • ANG antibody
    • ANG-1 antibody
    • ANG1 antibody
    • Angiopoietin-1 antibody
    • Angiopoietin1 antibody
    • ANGP1_HUMAN antibody
    • ANGPT 1 antibody
    • Angpt1 antibody
    • KIAA0003 antibody
    • OTTHUMP00000227592 antibody
    • OTTHUMP00000227599 antibody
    • OTTHUMP00000227600 antibody
    see all

References for Anti-Angiopoietin 1 antibody [171718] (ab49694)

ab49694 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"