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Product name Anti-Angiopoietin 2 antibody See all Angiopoietin 2 primary antibodies
Rabbit polyclonal to Angiopoietin 2
Specificity At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms.
Tested applications Suitable for:
ICC, WB more details
Mouse, Rat, Human
Synthetic peptide corresponding to 18 amino acids near the carboxy terminus of Human Angiopoietin 2 protein (O15123).
Human Liver Tissue Lysate.
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 2.5 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.Can be blocked with
Human Angiopoietin 2 peptide (ab172727).
Function Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Sequence similarities Contains 1 fibrinogen C-terminal domain.
Domain The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor.
Cellular localization Secreted.
Information by UniProt
AGPT 2 antibody
ANG 2 antibody
Anti-Angiopoietin 2 antibody images
Western blot - Anti-Angiopoietin 2 antibody (ab125692)
Lane 1 : Anti-Angiopoietin 2 antibody (ab125692) at 1 µg/ml Lane 2 : Anti-Angiopoietin 2 antibody (ab125692) at 2 µg/ml Lane 1 : Human liver tissue lysate Lane 2 : Human liver tissue lysate Lysates/proteins at 15 µg per lane. Predicted band size : 56 kDa
Immunocytochemistry - Anti-Angiopoietin 2 antibody (ab125692)
Immunohistochemistry of Angiopoietin 2 in mouse liver tissue with ab125692 antibody at 2.5 ug/mL.
References for Anti-Angiopoietin 2 antibody (ab125692)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"