Anti-Angiotensin Converting Enzyme 2 antibody (ab15349)


  • Product nameAnti-Angiotensin Converting Enzyme 2 antibody
    See all Angiotensin Converting Enzyme 2 primary antibodies
  • Description
    Rabbit polyclonal to Angiotensin Converting Enzyme 2
  • Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:


    , corresponding to Internal sequence amino acids 169 - 183 of Human ACE2. (Peptide available as ab15354.)

  • Positive control
    • Human kidney or human testis cell lysate
  • General notes

    No cross reactivity to ACE1


Associated products


Our Abpromise guarantee covers the use of ab15349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 97 kDa).Can be blocked with Human Angiotensin Converting Enzyme 2 peptide (ab15354).


  • FunctionCarboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
  • Tissue specificityExpressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
  • Sequence similaritiesBelongs to the peptidase M2 family.
  • Post-translational
    N-glycosylation on Asn-90 may limit SARS infectivity.
  • Cellular localizationSecreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACE 2 antibody
    • ACE related carboxypeptidase antibody
    • ACE-related carboxypeptidase antibody
    • ACE2 antibody
    • ACE2_HUMAN antibody
    • ACEH antibody
    • Angiotensin converting enzyme 2 antibody
    • Angiotensin converting enzyme homolog antibody
    • Angiotensin converting enzyme like protein antibody
    • Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody
    • Angiotensin I converting enzyme 2 antibody
    • Angiotensin-converting enzyme homolog antibody
    • DKFZP434A014 antibody
    • EC 3.4.17 antibody
    • metalloprotease MPROT 15 antibody
    • Metalloprotease MPROT15 antibody
    • OTTHUMP00000022963 antibody
    • Processed angiotensin-converting enzyme 2 antibody
    see all

Anti-Angiotensin Converting Enzyme 2 antibody images

  • Predicted band size : 97 kDa
  • ab15349 at 2µg/ml staining Angiotensin Converting Enzyme 2 in human kidney tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

References for Anti-Angiotensin Converting Enzyme 2 antibody (ab15349)

ab15349 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. As far as we are aware, cross reactivity with mouse has not yet been tested for use with ab15349 or any other ACE2 antibodies that we have. All species cross-reactivity information is stated on Abcam product datasheets, ...

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