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Product name Anti-Angiotensin II Type 1 Receptor antibody See all Angiotensin II Type 1 Receptor primary antibodies
Rabbit polyclonal to Angiotensin II Type 1 Receptor
Specificity ab124505 is specific for Angiotensin II Type 1 Receptor (AGTR1) and will not cross-react with AGTR2.
Tested applications Suitable for:
ICC/IF, WB, IHC-P more details
Mouse, Rat, Human
Synthetic peptide corresponding to Human Angiotensin II Type 1 Receptor (internal sequence).
Database link: P30556 (Peptide available as ab176148)
Mouse kidney tissue lysate; Mouse kidney tissue, mouse kidney cells.
Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 41 kDa.Can be blocked with
Angiotensin II Type 1 Receptor peptide (ab176148).
Use a concentration of 2.5 µg/ml.
Function Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Tissue specificity Liver, lung, adrenal and adrenocortical adenomas.
Involvement in disease Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
Sequence similarities Belongs to the G-protein coupled receptor 1 family.
Post-translational modifications C-terminal Ser or Thr residues may be phosphorylated.
Cellular localization Cell membrane.
Information by UniProt
Agtr 1 antibody
Anti-Angiotensin II Type 1 Receptor antibody images
Western blot - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
Lane 1 : Anti-Angiotensin II Type 1 Receptor antibody (ab124505) at 1 µg/ml Lane 2 : Anti-Angiotensin II Type 1 Receptor antibody (ab124505) at 2 µg/ml Lane 1 : Mouse kidney tissue lysate Lane 2 : Mouse kidney tissue lysate Lysates/proteins at 15 µg per lane. Predicted band size : 41 kDa
Immunocytochemistry/ Immunofluorescence-Anti-Angiotensin II Type 1 Receptor antibody(ab124505)
Immunofluorescence of AGTR1 in mouse kidney cells using ab124505 at 20 ug/ml.
Immunohistochemistry - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
Immunohistochemical analysis of mouse kidney tissue section labelling Angiotensin II Type 1 Receptor with ab124505, at 2.5 µg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
ab124505, at 2.5 µg/ml, staining Angiotensin II Type 1 Receptor in paraffin-embedded Mouse kidney tissue by Immunohistochemistry.
References for Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"