Anti-Angiotensin II Type 1 Receptor antibody (ab59018)


  • Product nameAnti-Angiotensin II Type 1 Receptor antibody
    See all Angiotensin II Type 1 Receptor primary antibodies
  • Description
    Goat polyclonal to Angiotensin II Type 1 Receptor
  • SpecificityAll reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Sheep, Rabbit, Guinea pig, Cow, Dog, Pig, Chimpanzee
  • Immunogen

    Synthetic peptide:


    , corresponding to internal sequence amino acids 227-240 of Human Angiotensin II Type 1 Receptor

  • Positive control
    • Mouse Liver lysate.



Our Abpromise guarantee covers the use of ab59018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesPeptide ELISA: antibody detection limit dilution 1:32,000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 41 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    • Tissue specificityLiver, lung, adrenal and adrenocortical adenomas.
    • Involvement in diseaseDefects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Post-translational
      C-terminal Ser or Thr residues may be phosphorylated.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AG2S antibody
      • Agtr 1 antibody
      • Agtr1 antibody
      • AGTR1_HUMAN antibody
      • Agtr1a antibody
      • AGTR1B antibody
      • Ang II antibody
      • Angiotensin II receptor type 1 antibody
      • Angiotensin II type-1 receptor antibody
      • Angiotensin receptor 1 antibody
      • Angiotensin receptor 1B antibody
      • AT 1B antibody
      • AT 1r antibody
      • AT1 antibody
      • At1a antibody
      • AT1AR antibody
      • AT1B antibody
      • AT1BR antibody
      • AT1R antibody
      • AT2R1 antibody
      • AT2R1A antibody
      • AT2R1B antibody
      • HAT1R antibody
      • Type 1 angiotensin II receptor antibody
      • Type 1B angiotensin II receptor antibody
      • Type-1 angiotensin II receptor antibody
      see all

    Anti-Angiotensin II Type 1 Receptor antibody images

    • Anti-Angiotensin II Type 1 Receptor antibody (ab59018) at 0.3 µg/ml + Mouse Liver lysate (35µg protein in RIPA buffer)

      Predicted band size : 41 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    References for Anti-Angiotensin II Type 1 Receptor antibody (ab59018)

    This product has been referenced in:
    • Goyal R  et al. Antenatal maternal protein deprivation: sexually dimorphic programming of the pancreatic renin-angiotensin system. J Renin Angiotensin Aldosterone Syst 14:137-45 (2013). Read more (PubMed: 22898440) »

    See 1 Publication for this product

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Mouse Cell (Kidney)
    Specification Kidney
    Fixative Formaldehyde
    Permeabilization Yes - 0.5% TX100
    Blocking step Serum as blocking agent for 20 minute(s) · Concentration: 5% · Temperature: 25°C

    Herr Dr. Vladimir Milenkovic

    Verified customer

    Submitted Feb 17 2009