Overview

  • Product name
  • Description
    Mouse polyclonal to Annexin A11
  • Host species
    Mouse
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-505 of Human Annexin A11 (NP_001148.1).

  • Positive control
    • Human pancreas tissue lysate; Annexin A11 transfected 293T cell lysate; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab166846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
  • Sequence similarities
    Belongs to the annexin family.
    Contains 4 annexin repeats.
  • Domain
    A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Cellular localization
    Cytoplasm. Melanosome. Nucleus envelope. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent.
  • Information by UniProt
  • Database links
  • Alternative names
    • 56 kDa autoantigen antibody
    • Annexin A11 antibody
    • Annexin XI antibody
    • Annexin-11 antibody
    • AnnexinA11 antibody
    • AnnexinXI antibody
    • ANX 11 antibody
    • ANX A11 antibody
    • ANX11 antibody
    • ANX11_HUMAN antibody
    • ANXA 11 antibody
    • ANXA11 antibody
    • Autoantigen 56 kD antibody
    • Calcyclin associated annexin 50 antibody
    • Calcyclin-associated annexin 50 antibody
    • CAP 50 antibody
    • CAP-50 antibody
    • CAP50 antibody
    • OTTHUMP00000059806 antibody
    see all

Images

  • Immunofluorescent analysis of HeLa cells, labeling Annexin A11 with ab166846 at 10µg/ml.
  • Anti-Annexin A11 antibody (ab166846) at 1 µg/ml + Human Pancreas tissue lysate at 50 µg

    Secondary
    Goat anti-Mouse IgG HRP at 1/2500 dilution

    Predicted band size: 54 kDa

  • All lanes : Anti-Annexin A11 antibody (ab166846) at 1 µg/ml

    Lane 1 : Annexin A11 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat anti-Mouse IgG HRP at 1/2500 dilution

    Predicted band size: 54 kDa

References

ab166846 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab166846.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up