Overview

  • Product nameAnti-Annexin A2 antibody [M298]
    See all Annexin A2 primary antibodies
  • Description
    Mouse monoclonal [M298] to Annexin A2
  • Tested applicationsWB, IP, ELISAmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Recombinant fragment, corresponding to the C-terminal region of Rat Annexin II

  • Positive control
    • PC12 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab86709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 36 kDa.
IP 1/50.
ELISA 1/2000.

Target

  • FunctionCalcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Post-translational
    modifications
    Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
    ISGylated.
  • Cellular localizationSecreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
  • Information by UniProt
  • Database links
  • Alternative names
    • Annexin A2 antibody
    • Annexin II antibody
    • Annexin II, heavy chain antibody
    • Annexin-2 antibody
    • ANX 2 antibody
    • ANX2 antibody
    • ANX2L4 antibody
    • ANXA2 antibody
    • ANXA2_HUMAN antibody
    • arylsulfatase B antibody
    • CAL1H antibody
    • Calpactin I heavy chain antibody
    • calpactin I heavy polypeptide (p36) antibody
    • Calpactin I heavy polypeptide antibody
    • Calpactin-1 heavy chain antibody
    • chromobindin 8 antibody
    • Chromobindin-8 antibody
    • Epididymis secretory protein Li 270 antibody
    • HEL S 270 antibody
    • LIP2 antibody
    • Lipocortin II antibody
    • LPC2 antibody
    • LPC2D antibody
    • P36 antibody
    • P36 protein antibody
    • PAP-IV antibody
    • placental anticoagulant protein IV antibody
    • Protein I antibody
    see all

Anti-Annexin A2 antibody [M298] images

  • Lane 1 : Anti-Annexin A2 antibody [M298] (ab86709) at 1/250 dilution
    Lane 2 : Anti-Annexin A2 antibody [M298] (ab86709) at 1/1000 dilution

    Lane 1 : Rat PC12 cell lysate
    Lane 2 : Rat PC12 cell lysate


    Observed band size : 36 kDa (why is the actual band size different from the predicted?)

References for Anti-Annexin A2 antibody [M298] (ab86709)

ab86709 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab86709.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"