General notesab94080 is a 293T cell transfected lysate in which Human Annexin II has been transiently over-expressed using a pCMV-Annexin II plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundDomain: A pair of annexin repeats may form one binding site for calcium and phospholipid.
Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
PTM: Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
Similarity: Belongs to the annexin family.
Contains 4 annexin repeats.