Overview

  • Product nameAnti-Annexin V antibody [AN5]
    See all Annexin V primary antibodies
  • Description
    Mouse monoclonal [AN5] to Annexin V
  • Tested applicationsSuitable for: Indirect ELISA, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human annexin V

  • Positive control
    • HeLa total cell extract.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab49823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA
WB
ICC/IF
  • Application notesICC/IF: Use at an assay dependent dilution.
    I-ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 0.5 - 1.0 µg/ml. Predicted molecular weight: 38 kDa.
    Array: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThis protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
    • Involvement in diseasePregnancy loss, recurrent, 3
    • Sequence similaritiesBelongs to the annexin family.
      Contains 4 annexin repeats.
    • DomainThe [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
      A pair of annexin repeats may form one binding site for calcium and phospholipid.
    • Post-translational
      modifications
      S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.
    • Information by UniProt
    • Database links
    • Alternative names
      • Anchorin CII antibody
      • Annexin 5 antibody
      • Annexin A5 antibody
      • Annexin V antibody
      • Annexin-5 antibody
      • ANX A5 antibody
      • ANX5 antibody
      • ANXA5 antibody
      • ANXA5_HUMAN antibody
      • Calphobindin I antibody
      • CBP-I antibody
      • Endonexin II antibody
      • ENX2 antibody
      • Lipocortin V antibody
      • PAP I antibody
      • PAP-I antibody
      • Placental anticoagulant protein 4 antibody
      • Placental anticoagulant protein I antibody
      • PLACENTAL PROTEIN 4 antibody
      • Pp4 antibody
      • Thromboplastin inhibitor antibody
      • VAC-alpha antibody
      • Vascular anticoagulant-alpha antibody
      see all

    Anti-Annexin V antibody [AN5] images

    • Anti-Annexin V antibody [AN5] (ab49823) at 0.5 µg/ml + HeLa total cell extract

      Secondary
      Goat Anti-Mouse, Alkaline Phosphatase conjugate

      Predicted band size : 38 kDa
      Observed band size : 29 kDa (why is the actual band size different from the predicted?)

    References for Anti-Annexin V antibody [AN5] (ab49823)

    This product has been referenced in:
    • Haedicke K  et al. Multiplexed in vivo fluorescence optical imaging of the therapeutic efficacy of photodynamic therapy. Biomaterials 34:10075-83 (2013). ICC/IF . Read more (PubMed: 24050876) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab49823.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"