1/100 - 1/250. Perform antigen retrieval before commencing with IHC staining protocol
1/100 - 1/250.
Is unsuitable for Flow Cyt or IP.
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Involvement in disease
Pregnancy loss, recurrent, 3
Belongs to the annexin family. Contains 4 annexin repeats.
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex. A pair of annexin repeats may form one binding site for calcium and phospholipid.
S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.
References for Anti-Annexin V antibody [EPR3979] (ab108321)
This product has been referenced in:
Campoy I et al. Exosome-like vesicles in uterine aspirates: a comparison of ultracentrifugation-based isolation protocols. J Transl Med14:180 (2016).
Read more (PubMed: 27317346) »
Liu B et al. Altered protein expression in gestational diabetes mellitus placentas provides insight into insulin resistance and coagulation/fibrinolysis pathways. PLoS One7:e44701 (2012).
Read more (PubMed: 22970290) »