Annexin V-PE Apoptosis Detection Reagent (ab14154)

  • FunctionThis protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
  • Involvement in diseasePregnancy loss, recurrent, 3
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainThe [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
    A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Post-translational
    modifications
    S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.
  • Information by UniProt
  • Alternative names
    • Anchorin CII
    • Annexin 5
    • Annexin A5
    • Annexin V
    • Annexin-5
    • ANX A5
    • ANX5
    • ANXA5
    • ANXA5_HUMAN
    • Calphobindin I
    • CBP-I
    • Endonexin II
    • ENX2
    • Lipocortin V
    • PAP I
    • PAP-I
    • Placental anticoagulant protein 4
    • Placental anticoagulant protein I
    • PLACENTAL PROTEIN 4
    • Pp4
    • Thromboplastin inhibitor
    • VAC-alpha
    • Vascular anticoagulant-alpha
    see all

Applications

Our Abpromise guarantee covers the use of ab14154 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
FM Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent dilution.

Protocols

References for Annexin V-PE Apoptosis Detection Reagent (ab14154)

ab14154 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. I am handling Charlottes enquiries in her absence. I have been in touch with a colleague from business development and I have been informed that the 1 x Annexin V Binding Buffer that Charlotte may have mentioned to you a...

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Thank you for your enquiry. You may keep the cells on ice for up to 30 minutes. We have not tried DAPI, but theoretically, cells can be stained with other dyes if no cell permeabilization is required. I hope this information helps. Please do ...

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