Anti-AP1M1 antibody (ab194384)
Key features and details
- Mouse polyclonal to AP1M1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-AP1M1 antibody
See all AP1M1 primary antibodies -
Description
Mouse polyclonal to AP1M1 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment (GST-tag) corresponding to Human AP1M1 aa 1-100. (NP_115882).
Database link: Q9BXS5 -
Positive control
- WB: recombinant human AP1M1, U-2 OS cell lysate,
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab194384 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 49 kDa.
|
Notes |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 49 kDa. |
Target
-
Function
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. -
Sequence similarities
Belongs to the adaptor complexes medium subunit family.
Contains 1 MHD (mu homology) domain. -
Post-translational
modificationsPhosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. -
Cellular localization
Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. - Information by UniProt
-
Database links
- Entrez Gene: 504310 Cow
- Entrez Gene: 8907 Human
- Entrez Gene: 11767 Mouse
- Entrez Gene: 306332 Rat
- Omim: 603535 Human
- SwissProt: Q2KJ81 Cow
- SwissProt: Q9BXS5 Human
- SwissProt: P35585 Mouse
see all -
Alternative names
- Adaptor protein complex AP-1 mu-1 subunit antibody
- Adaptor-related protein complex 1 mu-1 subunit antibody
- AP-1 complex subunit mu-1 antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab194384 has been referenced in 1 publication.
- Liu B et al. Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef-AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells. Front Immunol 10:2151 (2019). PubMed: 31572371