Overview

  • Product name
  • Description
    Rabbit polyclonal to AP1M2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Drosophila melanogaster, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to N terminal amino acids 1-50 of Human AP1M2

  • Positive control
    • 721_B

Properties

Applications

Our Abpromise guarantee covers the use of ab118934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Detects a band of approximately 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • Sequence similarities
    Belongs to the adaptor complexes medium subunit family.
    Contains 1 MHD (mu homology) domain.
  • Post-translational
    modifications
    Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.
  • Cellular localization
    Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adaptor protein complex AP-1 mu-2 subunit antibody
    • Adaptor protein complex AP1 mu2 subunit antibody
    • Adaptor related protein complex 1 mu2 subunit antibody
    • Adaptor-related protein complex 1 mu-2 subunit antibody
    • AP mu chain family member mu1B antibody
    • AP-1 complex subunit mu-2 antibody
    • AP-mu chain family member mu1B antibody
    • AP1 complex subunit mu2 antibody
    • AP1M2 antibody
    • AP1M2_HUMAN antibody
    • AP47 2 antibody
    • Clathrin assembly protein complex 1 medium chain 2 antibody
    • Golgi adaptor HA1/AP1 adaptin mu-2 subunit antibody
    • Golgi adaptor HA1/AP1 adaptin mu2 subunit antibody
    • HA1 47 kDa subunit 2 antibody
    • HSMU1B antibody
    • MU 1B antibody
    • Mu adaptin 2 antibody
    • Mu-adaptin 2 antibody
    • Mu1B adaptin antibody
    • Mu1B-adaptin antibody
    see all

Images

References

ab118934 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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