Anti-AP2 gamma antibody (ab31288)

Overview

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab31288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Can be blocked with Goat polyclonal to AP2 gamma (ab31288).
IHC-P Use a concentration of 2 - 3 µg/ml. In paraffin-embedded Human Skin shows nuclear staining of keratinocytes.

Target

  • FunctionSequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
  • Sequence similaritiesBelongs to the AP-2 family.
  • DomainThe WW-binding motif mediates interaction with WWOX.
  • Post-translational
    modifications
    Sumoylated on Lys-10; which inhibits transcriptional activity.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activating enhancer binding protein 2 gamma antibody
    • Activating enhancer-binding protein 2 gamma antibody
    • AP2-gamma antibody
    • AP2C_HUMAN antibody
    • AP2g antibody
    • AP2gamma antibody
    • ERF 1 antibody
    • ERF1 antibody
    • Estrogen receptor factor 1 antibody
    • hAP 2g antibody
    • hAP2g antibody
    • TFAP 2C antibody
    • TFAP 2G antibody
    • Tfap2c antibody
    • TFAP2G antibody
    • Transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma) antibody
    • Transcription factor AP 2 gamma antibody
    • Transcription factor AP-2 gamma antibody
    • Transcription factor ERF 1 antibody
    • Transcription factor ERF-1 antibody
    • Transcription factor ERF1 antibody
    see all

Anti-AP2 gamma antibody images

  • ab31288 staining AP2 gamma in Human skin. Steamed antigen retrieval with Tris/EDTA buffer pH 9 was performed. Antibody was detected by HRP-staining.

References for Anti-AP2 gamma antibody (ab31288)

ab31288 has not yet been referenced specifically in any publications.

Product Wall

Merci de votre intérêt pour les anti-AP2 gamma Abcam. Comme expliqué par téléphone, les anticorps ab31288, ab56030 et ab82788 n’ont pas encore été testé chez le rat et nous n’offrons pas d’échantillon gratuit à des fins de tests préliminaires. Cepen...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"