The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-AP2 gamma antibody (ab31288)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Activating enhancer binding protein 2 gamma
Activating enhancer-binding protein 2 gamma
Estrogen receptor factor 1
Transcription factor AP 2 gamma
Transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma)
Transcription factor AP-2 gamma
Transcription factor ERF 1
Transcription factor ERF-1
Transcription factor ERF1
FunctionSequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Sequence similaritiesBelongs to the AP-2 family.
DomainThe WW-binding motif mediates interaction with WWOX.
Post-translational modificationsSumoylated on Lys-10; which inhibits transcriptional activity.