Overview

  • Product name
  • Description
    Rabbit polyclonal to AP3M1
  • Specificity
    ab113104 may cross-react with AP3M2.
  • Tested applications
    Suitable for: ICC, WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide containing a 15 amino acid sequence from the C terminal region of Human AP3M1 (NP_036227).

  • Positive control
    • Human brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab113104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
  • Sequence similarities
    Belongs to the adaptor complexes medium subunit family.
    Contains 1 MHD (mu homology) domain.
  • Cellular localization
    Golgi apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adapter-related protein complex 3 mu-1 subunit antibody
    • AP-3 adapter complex mu3A subunit antibody
    • AP-3 complex subunit mu-1 antibody
    • AP3M1 antibody
    • AP3M1_HUMAN antibody
    • Clathrin adaptor complex AP3 mu 3A subunit antibody
    • Mu-adaptin 3A antibody
    • mu3A antibody
    • Mu3A-adaptin antibody
    see all

Anti-AP3M1 antibody images

  • Immunofluorescence of AP3M1 in mouse brain tissue with ab113104 at 20 ug/mL.
  • Lane 1 : Anti-AP3M1 antibody (ab113104) at 1 µg/ml
    Lane 2 : Anti-AP3M1 antibody (ab113104) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate


    Predicted band size : 47 kDa
  • Immunohistochemistry of AP3M1 in mouse brain tissue with ab113104 at 5 ug/mL.

References for Anti-AP3M1 antibody (ab113104)

This product has been referenced in:
  • Llinares E  et al. The AP-3 adaptor complex mediates sorting of yeast and mammalian PQ-loop-family basic amino acid transporters to the vacuolar/lysosomal membrane. Sci Rep 5:16665 (2015). WB . Read more (PubMed: 26577948) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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