Overview

  • Product nameAnti-APBA2 antibody
    See all APBA2 primary antibodies
  • Description
    Rabbit polyclonal to APBA2
  • Specificityab105396 is predicted not to cross-react with other X11 protein family members.
  • Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    An 18 amino acid synthetic peptide from near the center of Human APBA2 (NP_005494).

  • Positive control
    • Human brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab105396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 83 kDa.

Target

  • FunctionPutative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
  • Tissue specificityBrain.
  • Sequence similaritiesContains 2 PDZ (DHR) domains.
    Contains 1 PID domain.
  • DomainComposed of an N-terminal domain that binds STXBP1, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adapter protein X11beta antibody
    • Amyloid beta A4 precursor protein-binding family A member 2 antibody
    • APBA2 antibody
    • APBA2_HUMAN antibody
    • D15S1518E antibody
    • HsT16821 antibody
    • LIN 10 antibody
    • MGC:14091 antibody
    • MGC99508 antibody
    • Mint 2 antibody
    • Mint-2 antibody
    • MINT2 antibody
    • Neuron-specific X11L protein antibody
    • Neuronal Munc18-1-interacting protein 2 antibody
    • Phosphotyrosine binding/interacting domain (PTB) bearing protein antibody
    • X11 beta antibody
    • X11 like protein antibody
    • X11l antibody
    see all

Anti-APBA2 antibody images

  • Immunofluorescence of APBA2 in Human brain tissue with ab105396 at 20 ug/mL.
  • Immunohistochemistry of APBA2 in Human brain tissue with ab105396 at 10 μg/mL.

  • Lane 1 : Anti-APBA2 antibody (ab105396) at 1 µg/ml
    Lane 2 : Anti-APBA2 antibody (ab105396) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 83 kDa

References for Anti-APBA2 antibody (ab105396)

ab105396 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"